Chronic Allograft Lung Dysfunction (CLAD)
CLAD Treatment in India
Advanced diagnosis and management of chronic lung rejection after lung transplantation.
Chronic Allograft Lung Dysfunction (CLAD) is a major cause of long-term graft failure after lung transplantation. With increasing numbers of lung transplants performed in India, timely recognition and expert management of CLAD are essential to preserve lung function and quality of life.
Understanding Chronic Allograft Lung Dysfunction (CLAD)
Chronic Allograft Lung Dysfunction refers to a group of conditions characterized by progressive and irreversible decline in lung function following lung transplantation. It includes different phenotypes such as Bronchiolitis Obliterans Syndrome (BOS), Restrictive Allograft Syndrome (RAS), and mixed forms.
Early identification and targeted intervention can help slow progression and stabilize lung function.
Why CLAD Management Requires Specialized Expertise
Patients across India often face challenges such as:
- Delayed recognition of early CLAD symptoms
- Limited access to transplant-experienced pulmonologists
- Inadequate long-term lung function monitoring
- Overlap with infections common in Indian settings
"These challenges make expert, protocol-driven care critical for transplant recipients."
Why Early Diagnosis Matters
Untreated sleep disorders can increase the risk of serious health complications, including:
- Heart disease and stroke
- Hypertension and diabetes
- Worsening of existing lung disease
- Reduced work performance and increased accident risk
Timely evaluation and treatment can prevent long-term complications.
Comprehensive & Evidence-Based CLAD Management
Under the care of Dr. Srinivas Rajagopala, patients receive comprehensive, evidence-based management for CLAD, BOS, and RAS—aligned with international transplant guidelines and adapted to Indian clinical conditions.
Care focuses on early diagnosis, disease stabilization, and long-term graft preservation.
CLAD care includes a structured and systematic approach:
- Serial spirometry and lung function trend analysis
- High-resolution CT (HRCT) chest evaluation
- Exclusion of infections common in Indian settings
- Optimization of immunosuppressive therapy
- Reflux and aspiration assessment
- Pulmonary rehabilitation guidance
- Long-term follow-up for transplant recipients
This approach ensures accurate diagnosis and timely intervention.
Why Choose Dr. Srinivas Rajagopala?
- 20+ years of transplant expertise
- Leader in complex pulmonary care
- Ethical, patient-first approach
- Focused on long-term outcomes
When to Consult a CLAD Specialist in India
You should seek specialist evaluation if you:
- Have undergone lung transplantation in India or abroad
- Are experiencing progressive breathlessness after transplant
- Have a documented drop in FEV₁ of 20% or more
- Have been diagnosed with BOS, RAS, or chronic lung rejection
- Are seeking a second opinion for CLAD management in India